Hormones and HRT
HRT risks & benefits
Worried about HRT risks? Unclear about the benefits? We answer your questions and provide expert advice.
Other specialist services
Existing patient services
About
Contact us
Other specialist services
Everything you need to know about Testogel 40.5mg gel
Everything you need to know about Testogel 40.5mg gel
While often mischaracterised as a "male" hormone, testosterone is an essential component of a woman’s endocrine profile. Produced by the ovaries and adrenal glands, it plays a critical role in maintaining energy, bone density, and sexual function. At Menopause Care, we understand that for many women, oestrogen and progesterone are only part of the story. If you are experiencing persistent lethargy or a loss of "joie de vivre" despite being on standard HRT, topical testosterone for women may be the missing link.
If you are considering Testogel as part of your HRT plan, here is what you need to know about how to use it, its benefits, and possible side effects.
Medically reviewed by Dr. Liz Andrew
BMS Accredited Doctor
Reviewed: 24/02/2025 Published: 25/02/2025
The basics
Key information about Testogel
Benefits of Testogel
In the UK, the guidelines only refer to testosterone treatment being recommended when women have persistent struggles with low libido after trying HRT. There is evidence showing that testosterone replacement in menopausal women can:
- Boost libido – Helps improve sexual desire and responsiveness
There is emerging evidence to suggest that it also helps with:
- Increased energy levels – Reduces fatigue and enhances overall vitality
- Enhanced cognitive function – Supports memory, focus, and mental clarity
- Muscle and bone health – Helps maintain muscle mass and reduces the risk of osteoporosis
- Mood symptoms – Can help reduce feelings of low mood, anxiety, and irritability
Learn more about your treatment options
Book a complementary discovery call with our patient expert Jane James. Jane can help you by:
- Explaining the clinical pathway and how oestrogen patches can be prescribed through Menopause Care
- Offering guidance as to whether you may benefit from hormone replacement therapy (HRT)
- Share personal insight and other patient experiences of oestrogen treatment (non-clinical advice)
- Offering compassionate support and a safe, confidential space to openly discuss your concerns
How to Apply Testogel for Female Libido: A Specialist Guide
Correct application is vital for the success of your testosterone replacement for women.
Side effects of Testogel
Common side effects of Androfemme can include:
- Mild increase in facial or body hair (usually fine, light hair and on the application site
- Oily skin or mild acne
- Changes in mood – slight irritability or emotional shifts
- Headaches
- Skin irritation at the application site
Less Common Side Effects of Androfemme are:
- Hair thinning – this is rare but can happen if testosterone levels become too high
- Deepening of the voice – this is very uncommon at the correct female dose
Testogel explained
Dr. Liz Andrew explains Testogel on one of our latest webinars all about HRT and testosterone products. You can watch the fully recorded webinar on YouTube.
Testogel dosages explained
Testogel 40.5mg gel comes in individual sachets and is designed for testosterone replacement therapy. Women require a much lower dose than men, so the amount used needs to be carefully measured. Finding the correct Testogel dosage for menopause is a delicate science. Because Testogel sachets are designed for male levels, your doctor will guide you on how to measure your dose and how to reseal the sachet (using a clip) to last 8 to 10 days.
0.25 sachet
Dosage level
Provides 10mg testosterone. This is considered a high dose.
Application frequency
Applied daily
0.2 sachet
Dosage level
Provides 8mg testosterone. This is considered a moderate dose.
Application frequency
Applied daily
0.15 sachet
Dosage level
Provides 6mg testosterone. This is the moderate-low dose, commonly prescribed for women.
Application frequency
Applied daily
0.1 sachet
Dosage level
Provides 4mg testosterone. This is a low dose, used for maintenance or for women sensitive to testosterone
Application frequency
Applied daily
Dr. Liz Andrew
Your dosage level of Testogel can vary depending on the individual. This should be explained clearly by your doctor before starting medication and also throughout your treatment if you are making any adjustments.
Our doctors provide holistic care for all menopause symptoms
Hormones and HRT
Bio identical vs body identical hormone replacement therapy
Let's debunk some myths around HRT and 'bioidentical hormones'.
Hormones and HRT
HRT and weight loss
Understand how HRT impacts weight during the menopause.
Hormones and HRT
Testosterone and menopause
Not all women need testosterone replacement during menopause, but it can be helpful if levels are low. Find out more in this guide.
Contact us