Anxiety in menopause
Anxiety in menopause
Anxiety is one of the most common symptoms of menopause. Find out more about what causes it, possible treatments, and how we can help.

Medically reviewed by Dr. Liz Andrew
BMS Accredited Doctor

How common is this symptom?
10-15%
Of menopausal women report experiencing anxiety
15-50%
Of perimenopausal and postmenopausal women report experiencing anxiety
40%
Increased risk of experiencing anxiety during peri-menopause
Ref: https://committees.parliament.uk/writtenevidence/39340/pdf/
https://www.theguardian.com/society/2024/may/01/perimenopausal-women-have-40-higher-risk-of-depression-study-suggests

What is anxiety?
Anxiety is a feeling of unease, worry, or fear, often accompanied by physical symptoms such as a racing heart, shortness of breath, or dizziness. It can feel persistent and hard to explain, and for many women, it arrives without any obvious external cause.
For a significant number of women, anxiety is the first sign that something hormonal is changing. It can appear before periods become irregular, before hot flushes begin, and long before menopause feels like a relevant word. The brain is highly sensitive to fluctuations in oestrogen and progesterone. These hormones influence the neurotransmitters that regulate mood and stress responses, including serotonin and GABA. When they begin to shift, the effect on how you feel can be profound.
This is not a psychological response to getting older. It is a biological one.
Learn more about this symptom
Hormonal fluctuations are the primary driver of anxiety in menopause. Oestrogen plays a crucial role in serotonin production, a key neurotransmitter that stabilises mood. When oestrogen levels drop, serotonin production can decrease, leading to mood instability and heightened anxiety. Additionally, physical changes like hot flushes, night sweats or disrupted sleep can exacerbate stress levels.
The effect is rarely linear. The peaks and troughs of fluctuating hormones can trigger significant emotional disturbance, which is why anxiety during perimenopause often feels different from ordinary worry or stress.
It tends to feel more biological: a persistent sense of dread or unease that has no clear external cause. Many women describe a sudden loss of confidence in situations where they previously felt entirely at ease.
Other contributing factors can include:
- Life stressors typical of midlife, such as career demands or caregiving responsibilities.
- The psychological impact of aging and bodily changes.
- Underlying medical conditions or pre-existing anxiety disorders.
Anxiety can also develop or intensify alongside cycle changes. If yours has worsened at the same time your periods have become heavier, lighter, or less predictable, this is a recognised pattern of perimenopause and worth discussing with a specialist.
Both perimenopausal and menopausal anxiety does not always present as classic worry. Women describe a persistent tightness in the chest, an inability to switch off, or a sense of impending dread that is difficult to rationalise. Some experience panic attacks, which can occur during the day or, more commonly, wake them from sleep. Others describe waking in the early hours with a racing heart, which is often related to overnight drops in oestrogen or blood sugar, triggering a cortisol response.
Palpitations and other physical sensations associated with perimenopause, such as temperature changes or what some describe as an electric feeling under the skin, can also fuel health anxiety. Because these sensations are unfamiliar, it is common to become increasingly alert to them, which compounds the anxiety itself.
Mood changes are often the earliest sign that hormones are shifting. Irritability, low motivation, a sense of reduced resilience, and a loss of the emotional steadiness that once felt natural are all common features of the perimenopausal transition, and all have a hormonal basis.
Hormone Replacement Therapy (HRT) is a proven method for alleviating anxiety symptoms during menopause.
By stabilising hormone levels, HRT:
- Restores oestrogen to promote serotonin balance, reducing mood swings and anxiety
- Addresses physical symptoms like hot flushes and poor sleep, which can worsen anxiety
- Improves your overall emotional resilience
Where appropriate, treatment typically includes transdermal oestrogen alongside body-identical progesterone for women with a womb. Progesterone is broken down in the body into a compound called allopregnanolone, which acts on GABA receptors in the brain and has a naturally calming effect. Many women notice an improvement in both sleep and anxiety relatively early in treatment, though the full effect builds over time.
At Menopause Care, we provide personalised plans that may include HRT or medication alongside other holistic treatments. Everything is tailored to your individual symptoms and personal health history. What helps at one stage of the transition may need adjusting at another.
While HRT is effective for many women, there are also non-hormonal treatments available to help manage anxiety during menopause.
- Non-hormonal medications: SSRIs or beta blockers may be helpful to calm anxiety and support mood symptoms for some women when HRT may not be the right choice.
- Cognitive Behavioral Therapy (CBT): CBT can help you identify negative thought patterns and develop healthy coping strategies. It’s a well-established method for managing anxiety.
- Mindfulness and meditation: Practices such as mindfulness meditation and yoga can reduce anxiety by promoting relaxation and reducing stress levels.
- Exercise: Regular physical activity, particularly aerobic exercises, can help regulate stress hormones and release feel-good endorphins, improving overall mood.
- Diet and supplements: Incorporating foods rich in magnesium glycinate, omega-3s, and B vitamins can support your nervous system and reduce feelings of anxiety. Herbal remedies like valerian root or passionflower can also provide a calming effect.
For most women, yes. With the right clinical support and treatment, the background noise of hormonal anxiety does recede. It is not something you need to simply manage or push through. Understanding that it has a physiological cause is the first step, and treating that cause effectively is what specialist care is designed to do.
A few lifestyle tips that can help
- 1
Practice deep breathing
Take five minutes each day to focus on your breath. Deep breathing helps to activate the parasympathetic nervous system, calming your body and reducing anxiety.
- 2
Stay active
Incorporate regular exercise into your routine. Even a 15-minute walk can help to reduce anxiety by releasing endorphins and improving overall mood.
- 3
Create a sleep routine
Anxiety often worsens with poor sleep. Establish a relaxing bedtime routine, limit your caffeine intake in the afternoon, and aim for consistent sleep hours.
How we can help
At Menopause Care, we specialise in helping women navigate the emotional and physical challenges of menopause, including anxiety. Here is how we can assist:

Our expert team will listen to your concerns, assess your symptoms and recommend treatment options tailored to your needs. Whether it’s HRT, alternative medication or a holistic treatment plan, we are here to help you feel better.

We do not take a one-size-fits-all approach. Treatment for anxiety in perimenopause may involve HRT, adjustment of existing hormonal treatment, non-hormonal medication, psychological support, or a combination. Your plan is built around you and reviewed over time as your symptoms change.

Managing hormonal symptoms is an ongoing process. For women who want more consistent clinical oversight, particularly during the perimenopause phase when symptoms can fluctuate considerably, we offer also a monthly doctor subscription that provides continuity with the same clinician.
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