Everything you need to know about Androfeme

Androfeme is a testosterone replacement therapy designed specifically for women. It is a transdermal cream, meaning it is absorbed through the skin rather than taken orally.

If you are considering Androfeme as part of your HRT plan, here is what you need to know about how to use it, its benefits, and possible side effects.

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Medically reviewed by Dr. Liz Andrew

BMS Accredited Doctor

iconReviewed: 24/02/2025 Published: 25/02/2025
The basics

Key information about Androfeme

Benefits of Androfeme

Replacing testosterone with Androfeme is best known for the benefits to sexual function:

Boosts libido – Helps improve sexual desire, arousal, and satisfaction

Emerging research demonstrates the additional benefits of testosterone therapy in the following areas:

  • Increased energy levels – Reduces fatigue and enhances overall vitality
  • Enhanced cognitive function – Supports memory, focus, and mental clarity
  • Muscle and bone health – Helps maintain muscle mass and reduces the risk of osteoporosis
  • Mood symptoms – Can reduce feelings of low mood, anxiety, and irritability.

Learn more about your treatment options

Book a complementary discovery call with our patient expert Jane James. Jane can help you by:

  • Explaining the clinical pathway and how oestrogen patches can be prescribed through Menopause Care
  • Offering guidance as to whether you may benefit from hormone replacement therapy (HRT)
  • Share personal insight and other patient experiences of oestrogen treatment (non-clinical advice)
  • Offering compassionate support and a safe, confidential space to openly discuss your concerns
Simple and flexible care for your symptoms

Learn more about our personalised plans

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How and where to use Androfeme?

Side effects of Androfeme

Common side effects of Androfeme can include:

  • Mild increase in facial or body hair (usually fine, light hair and on the application site
  • Oily skin or mild acne
  • Changes in mood – slight irritability or emotional shifts
  • Headaches

Less Common Side Effects of Androfeme are:

  • Hair thinning – this is rare but can happen if testosterone levels become too high
  • Deepening of the voice – this is very uncommon at the correct female dose

Androfeme dosages explained

Each 1mL of Androfeme contains 10mg of testosterone. The usual prescribed dose is 0.5mL per day, delivering 5mg of testosterone. However, the dose can vary depending on individual needs and doctor recommendations. Always ask your doctor if you have any questions about the dosing.
0.25mL
Dosage level

Provides 2.5mg testosterone. This is considered a low starting dose.

Application frequency

Applied daily

0.5mL
Dosage level

Provides 5mg testosterone. This is the most common dose for women.

Application frequency

Applied daily

0.75mL
Dosage level

Provides 7.5mg testosterone. This is a higher dose and sometimes used if lower doses are not effective.

Application frequency

Applied daily

1mL
Dosage level

Provides 10mg testosterone. This is a high dose which is rarely prescribed.

Application frequency

Applied daily and requires close monitoring.

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Dr. Liz Andrew
Your dosage level of Androfeme can vary depending on the individual. This should be explained clearly by your doctor before starting medication and also throughout your treatment if you are making any adjustments.
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Androfeme explained

Dr. Liz Andrew explains Androfeme on one of our latest webinars all about HRT and testosterone products. You can watch the fully recorded webinar on YouTube.