Everything you need to know about Oestrogel

Learn more about Oestrogel, and whether it’s something you might want to try as part of your HRT plan. Oestrogel is a form of oestrogen replacement therapy. It is a transdermal gel, meaning it is absorbed through the skin rather than taken as a pill.

If you are considering Oestrogel as part of your HRT plan, here is what you need to know about how to use it, its benefits, and possible side effects.

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Medically reviewed by Dr. Liz Andrew

BMS Accredited Doctor

iconReviewed: 19/02/2025 Published: 20/02/2025
The basics

Key information about Oestrogel

Benefits of Oestrogel

Oestrogel is widely used due to its effectiveness and adaptability, having an impact on all 40 symptoms of menopause.

Key benefits of oestrogel:

  • Effective Symptom Relief: Targets hot flushes, night sweats, and vaginal dryness.
  • Restored Sleep & Mood: Helps stabilize hormone fluctuations to improve sleep quality and reduce anxiety.
  • Enhanced Safety Profile: Carries a lower risk of blood clots compared to oral HRT.
  • Bone & Heart Support: Reduces the long-term risk of osteoporosis.
  • Stable Hormone Delivery: Provides a steady release of oestrogen for more consistent symptom control.
  • Gentle on the System: Bypasses the digestive tract, making it ideal for those with sensitive stomachs.
  • Tailored to You: Offers flexible dosing and better tolerability for those sensitive to synthetic hormones.
  • Simple & Non-Invasive: Easy to apply as part of your daily routine.
Simple and flexible care for your symptoms

Learn more about our personalised plans

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How and where to apply oestrogel correctly

In this short clip menopause expert Dr Eloise Elphinstone explains her top tips when using Oestrogel

Learn more about your treatment options

Book a complementary discovery call with our patient expert Jane James. Jane can help you by:

  • Explaining the clinical pathway and how oestrogen patches can be prescribed through Menopause Care
  • Offering guidance as to whether you may benefit from hormone replacement therapy (HRT)
  • Share personal insight and other patient experiences of oestrogen treatment (non-clinical advice)
  • Offering compassionate support and a safe, confidential space to openly discuss your concerns

Side effects of Oestrogel

Common side effects can include:

  • Breast tenderness or pain
  • Bloating
  • Abdominal pain
  • Mild headaches
  • Mood changes
  • Skin irritation at application site

Less common risks:

  • Blood clots (lower risk than oral HRT)
  • Hormonal fluctuations
  • Irregular bleeding (especially early in treatment)

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Oestrogel explained

Dr. Laura Cawley and Dr. Liz Andrew explain Oestrogel on one of our latest webinars all about HRT and testosterone products. You can watch the fully recorded webinar on YouTube.

Oestrogel vs other HRT options

Choosing the right HRT depends on your lifestyle and medical profile.
Oestrogel vs tablets
Lower risk of clotting

More stable hormone levels

Avoids liver metabolism

Oestrogel vs patches
More flexible dosing

No adhesive irritation

Easier to adjust daily

Oestrogel vs sprays
Similar absorption

Gel allows broader application area

At Menopause Care, we help you compare options and choose the most suitable treatment for you..
Frequently asked questions

Everything you want to know about Oestrogel