HRT - Oestrogen Spray
HRT - Oestrogen Spray
Oestrogen spray is a body identical oestrogen, derived from plants (yams), which is a spray onto the skin and is gradually absorbed. There is one option of oestrogen spray which is Lenzetto.
Medically reviewed by Dr. Liz Andrew
BMS Accredited Menopause Doctor
Reviewed: 19/02/2025 Published: 21/02/2025
Oestrogen spray we prescribe
Lenzetto is a body identical oestrogen product which contains small amounts of a natural hormone called estradiol.
It is an easy-to-use, daily spray. You apply it to the forearm or inner thigh, on clean dry skin and it dries quickly. It gradually passes through the skin into your bloodstream where it then travels throughout the body to help with menopause symptoms.
Each device contains 56 sprays but the number of sprays you use each day will depend on the severity of your symptoms and your doctor’s instructions. It can be difficult to know when it runs out, so marking off sprays on the box can be helpful.
Although it dries within around 2 minutes and leaves no residue, women should wait a few minutes before dressing and avoid swimming or bathing within the first few hours of using it. If using sun cream, this must be applied at least an hour before using Lenzetto.
In women who still have a womb, it needs to be used alongside progesterone to provide endometrial protection.
Learn more about your treatment options
Book a complementary discovery call with our patient expert Jane James. Jane can help you by:
- Explaining the clinical pathway and how oestrogen patches can be prescribed through Menopause Care
- Offering guidance as to whether you may benefit from hormone replacement therapy (HRT)
- Share personal insight and other patient experiences of oestrogen treatment (non-clinical advice)
- Offering compassionate support and a safe, confidential space to openly discuss your concerns
