Hormones and HRT
HRT risks & benefits
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Everything you need to know about Vagirux pessaries
Everything you need to know about Vagirux pessaries
Vagirux is a low-dose vaginal oestrogen therapy designed to relieve vaginal atrophy, a common condition caused by declining oestrogen levels during menopause. Vaginal atrophy leads to thinning, dryness, and increased fragility of the vaginal tissues, which can cause irritation, discomfort, and urinary symptoms.
Medically reviewed by Dr. Liz Andrew
BMS Accredited Doctor
Reviewed: 14/03/2025 Published: 20/03/2025.png)
The basics
Key Information About Vagirux (10mcg Estradiol Pessaries)
Vagirux is prescribed to treat vaginal and urinary symptoms of menopause, including:
- Vaginal dryness, itching, and discomfort
- Pain during intercourse
- Recurrent urinary tract infections (UTIs)
- Increased urinary urgency or frequency
- Mild pelvic organ prolapse symptoms
By replenishing oestrogen levels locally, Vagirux improves the health of vaginal tissues and supports bladder function.
Yes, Vagirux is considered safe for long-term use when prescribed appropriately. Since it is a local oestrogen, it does not significantly increase oestrogen levels in the bloodstream, meaning it does not carry the same risks as systemic HRT, such as an increased risk of blood clots or breast cancer.
However, if you have a history of breast cancer, blood clots, or other medical concerns, speak with your doctor before starting Vagirux.
Vagirux contains 10mcg estradiol—the same as Vagifem—but differs in its applicator design. It provides the same effectiveness, but some women prefer one over the other based on ease of use.
Yes, our doctors and nurses can prescribe Vagirux during consultations.
Benefits of Vagirux
- Restores vaginal moisture – easing irritation and dryness
- Supports bladder health – reducing urinary symptoms and UTIs
- Helps strengthen vaginal tissues – useful for mild prolapse symptoms
- Can be used long-term – with minimal systemic absorption
- Simple and discreet – easy-to-use, pre-filled applicator
Vagirux side effects
- Mild vaginal irritation (burning, itching, or increased discharge)
- Breast tenderness
- Headaches
- Bloating or mild abdominal discomfort
- Spotting or light bleeding (especially in the first few months)
As a low dose medication, many women do not get side effects. If you do experience side effects, they will improve as your body adjusts. If they persist or worsen, consult your doctor for further advice.
There is no evidence that Vagirux, or any other vaginal oestrogen treatments, cause weight gain. Local oestrogen does not affect metabolism or body fat distribution like systemic HRT.
Some women notice an improvement within a few days, but for full benefits, it may take several weeks of consistent use.
Vaginal oestrogen medications do not reverse prolapse, but they can strengthen and improve vaginal tissue elasticity, which may help with mild prolapse symptoms.
Both are effective, and the choice depends on what feels most comfortable for you.
- Pessaries deliver a precise dose directly into the vagina.
- Creams cover a larger surface area and can be used externally.
The treatment that your doctor recommends will depend on your personal symptoms and preferences.
Both contain estriol (Ovestin) or estradiol (Vagirux), but Vagirux pessaries deliver a slightly higher dose per application.
4 tips to help you
How to use Vagirux
- 1
Insert using the applicator
One pessary is inserted into the vagina, usually daily for the first two weeks, then reduced to twice a week for maintenance.
- 2
Consistency is key
Regular use ensures the best symptom relief
- 3
Wash hands before and after use
To maintain hygiene and avoid irritation
- 4
For vaginal use only
The pessary should never be swallowed
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